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A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)


Active: Yes
Cancer Type: Breast Cancer NCT ID: NCT04961996
Trial Phases: Phase III Protocol IDs: GO42784 (primary)
NCI-2021-09253
2021-000129-28
Eligibility: 18 Years and older, Male and Female Study Type: Treatment
Study Sponsor: Hoffmann-La Roche
NCI Full Details: http://clinicaltrials.gov/show/NCT04961996

Summary

This is a Phase III, global, randomized, open-label, multicenter, study evaluating the
efficacy and safety of adjuvant giredestrant compared with endocrine therapy of
physician's choice in participants with medium- and high-risk Stage I-III histologically
confirmed estrogen receptor (ER)-positive and human epidermal growth factor receptor 2
(HER2)-negative early breast cancer.

In addition, an open-label exploratory substudy will explore the safety and efficacy of
giredestrant in combination with abemaciclib in a subset of the primary study population.

Treatment Sites in Georgia

Northwest Georgia Oncology Centers - Cobb Hospital (Hiram)
144 Bill Carruth Parkway
Suite 3100
Hiram, GA 30141
770-281-5131
www.ngoc.com



Northwest Georgia Oncology Centers - Tanner Medical Center Villa Rica
157 Clinic Avenue
Suite 101 and Suite 102
Carrollton, GA 30117
770-281-5101
www.ngoc.com

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