Genetic Testing in African Americans (GTM-I)
Endometrial Cancer
Ovarian Cancer
Summary
This is a pilot/feasibility study to conduct genetic testing using tumor/blood samples of African American and Caucasian patients with ovarian and endometrial cancer following surgery at AU Health Medical Center. The aim of the pilot/feasibility study is to sequence a panel of cancer genes on paired tumor/blood (germline) samples of patients with ovarian and endometrial tumors at a two-week time point following surgery at AU Medical Center. While paired testing of tumor and blood (germline) provides direct clinical value to patients, investigators propose to study whether investigators can define and overcome such minority barriers among the Georgia Cancer Center (GCC)/AU Health Medical Center (AUMC) patient population.
Objectives
The purpose of this study is to identify genetic mutations using a sequence a panel to detect cancer genes on paired tumor/blood (germline) samples particularly (AA) patients with ovarian, endometrial, fallopian or primary peritoneal carcinoma as AA individuals with cancer are less prone to accept a recommendation to undergo genetic testing. Approximately 30 subjects will participate in this study at Georgia Cancer Center/AU Health Medical Center.
Eligibility
Inclusion Criteria:
- Age ≥ 18 years of age.
- New diagnosis of ovarian, endometrial, fallopian, or primary peritoneal carcinoma.
- Diagnostic procedure performed at AU Health Medical Center.
- Adequate tissue is available for the tumor testing component (e.g., cytology and FNA samples are typically not adequate, whereas core biopsies and open biopsies usually are adequate.
- Consent at first post-biopsy outpatient clinic visit (typically about 2 weeks).
- Ability to provide informed consent in English.
Exclusion Criteria:
There are no exclusion criteria
Treatment Sites in Georgia
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